ニュース
最近の発表論文
2024年10月6日
Majima M, Matsuda Y, Watanabe SI, Ohtaki Y, Hosono K, Ito Y, Amano H. Prostanoids Regulate Angiogenesis and Lymphangiogenesis in Pathological Conditions. Cold Spring Harb Perspect Med. 2024 Apr 2:a041182. doi: 10.1101/cshperspect.a041182. Epub ahead of print. PMID: 38565267.
Hosono K, Yamashita A, Tanabe M, Ito Y, Majima M, Tsujikawa K, Amano H. Deletion of RAMP1 Signaling Enhances Diet-induced Obesity and Fat Absorption via Intestinal Lacteals in Mice. In Vivo. 2024 Jan-Feb;38(1):160-173. doi: 10.21873/invivo.13422. PMID: 38148085.
Majima M, Hosono K, Ito Y, Amano H, Nagashima Y, Matsuda Y, Watanabe SI, Nishimura H. A biologically active lipid, thromboxane, as a regulator of angiogenesis and lymphangiogenesis. Biomed Pharmacother. 2023 Jul;163:114831. doi: 10.1016/j.biopha.2023.114831. Epub 2023 May 8. PMID: 37150029.
Tanabe M, Hosono K, Yamashita A, Ito Y, Majima M, Narumiya S, Kusano C, Amano H. Deletion of TP signaling in macrophages delays liver repair following APAP-induced liver injury by reducing accumulation of reparative macrophage and production of HGF. Inflamm Regen. 2024 Oct 3;44(1):43. doi: 10.1186/s41232-024-00356-z. PMID: 39363292; PMCID: PMC11451145.
2022年度 基盤研究(C)に採択されました(研究代表者;馬嶋正隆)
リンパ管・リンパ組織の可塑性を制御する神経ペプチド解析と治療応用のための基盤研究
最近の発表論文
Satoh M, Iizuka M, Majima M, Ohwa C, Hattori A, Van Kaer L, Iwabuchi K. Adipose invariant NKT cells interact with CD1d-expressing macrophages to regulate obesity-related inflammation. Immunology. 2022 Feb 8. doi: 10.1111/imm.13447. Epub ahead of print. PMID: 35137411.
最近の発表論文
Roles of thromboxane receptor signaling in enhancement of lipopolysaccharide-Induced lymphangiogenesis and lymphatic drainage function in diaphragm. H Matsuda, Y Ito, K Hosono, S Tsuru, T Inoue, S Nakamoto, C Kurashige, M Hirashma, S Narumiya, H Okamoto, M Majima. Arterioscler Thromb Vasc Biol. 2021 41(4):1390-1407.
Thromboxane receptor, TP signaling enhances lymphangiogenesis acting on macrophages and T cells in the inflamed tissues. This is novel activity of TP signaling. TP signaling represents a promising target for controlling
lymphangiogenesis.